Anti-CD34 antibody
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概述
- 产品描述The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. However, little is known about its exact function. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia, whereas the L-selectin to which it binds is on the T cell. Conversely, under other circumstances CD34 has been shown to act as molecular "Teflon" and block mast cell, eosinophil and dendritic cell precursor adhesion, and to facilitate opening of vascular lumina. CD34 may also play a more selective role in chemokine-dependent migration of eosinophils and dendritic cell precursors. Regardless of its mode of action, under all circumstances CD34, and its relatives podocalyxin and endoglycan, facilitates cell migration.
- 产品名称Anti-CD34 antibody
- 分子量120 kDa
- 种属反应性Human,Mouse
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Membrane.
- 其它名称CD34 antibody
CD34 antigen antibody
CD34 molecule antibody
CD34_HUMAN antibody
Cluster designation 34 antibody
Hematopoietic progenitor cell antigen CD34 antibody
HPCA1 antibody
Mucosialin antibody
OTTHUMP00000034733 antibody
OTTHUMP00000034734 antibody
more
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应用
WB: 1:500-2,000
IHC-P: 1:100-1:500
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Fig1: Western blot analysis of CD34 on TF-1 cell (1) and human brain tissue (2) lysates using anti-CD34 antibody at 1/1,000 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-CD34 antibody. Counter stained with hematoxylin.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!