Anti-DLL4 antibody
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概述
- 产品描述The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.
- 产品名称Anti-DLL4 antibody
- 分子量74 kDa (Predicted band size)
- 种属反应性Human,Mouse
- 验证应用WB,ICC,IHC-P,FC
- 抗体类型兔多抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein A purified.
- 亚细胞定位Cell membrane.
- 其它名称AOS6 antibody
Delta 4 antibody
delta 4 precursor antibody
Delta ligand 4 antibody
delta ligand 4 precursor antibody
Delta like 4 antibody
Delta like 4 homolog antibody
Delta like 4 protein antibody
Delta like canonical Notch ligand 4 antibody
Delta like protein 4 antibody
Delta-like 4 (Drosophila) antibody
Delta-like protein 4 antibody
Delta4 antibody
DLL 4 antibody
Dll4 antibody
DLL4_HUMAN antibody
Drosophila Delta homolog 4 antibody
hdelta2 antibody
Homeobox protein DLL-4 antibody
MGC126344 antibody
Notch ligand delta 2 antibody
Notch ligand DLL4 antibody
Notch ligand DLL4 precursor antibody
XDLL-4 antibody
more
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应用
WB: 1:500-1:1,000
ICC: 1:50-1:200
IHC-P: 1:50-1:200
FC: 1:50-1:100
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Fig1: Western blot analysis of DLL4 on mouse placenta tissue (1) and HUVEC (2) lysate using anti-DLL4 antibody at 1/500 dilution.
Fig2: ICC staining DLL4 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining DLL4 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: ICC staining DLL4 in PMVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig5: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-DLL4 antibody. Counter stained with hematoxylin.
Fig6: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-DLL4 antibody. Counter stained with hematoxylin.
Fig7: Flow cytometric analysis of HUVEC cells with DLL4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
