Anti-SCNN1G antibody
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概述
- 产品描述Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
- 产品名称Anti-SCNN1G antibody
- 分子量74 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC,IHC-P,FC
- 抗体类型兔多抗
- 免疫原Recombinant protein within human SCNN1G aa 250-350.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Plasma membrane.
- 其它名称Amiloride sensitive epithelial sodium channel gamma subunit antibody
Amiloride sensitive sodium channel subunit gamma antibody
Amiloride-sensitive sodium channel subunit gamma antibody
BESC3 antibody
ENaC gamma subunit antibody
ENaCG antibody
ENaCgamma antibody
Epithelial Na(+) channel subunit gamma antibody
Epithelial Na+ channel subunit gamma antibody
Gamma ENaC antibody
Gamma NaCH antibody
Gamma-ENaC antibody
Gamma-NaCH antibody
Nonvoltage gated sodium channel 1 subunit gamma antibody
Nonvoltage-gated sodium channel 1 subunit gamma antibody
PHA 1 antibody
PHA1 antibody
SCNEG antibody
SCNN 1G antibody
SCNN1G antibody
SCNNG_HUMAN antibody
Sodium channel epithelial 1 gamma subunit antibody
Sodium channel non voltage gated 1 gamma subunit antibody
Sodium channel nonvoltage gated 1 gamma antibody
more
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应用
WB: 1:500-1:2,000
ICC: 1:50-1:200
IHC-P: 1:50-1:200
FC: 1:50-1:100
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Fig1: Western blot analysis of SCNN1G on A431 cell lysate using anti-SCNN1G antibody at 1/1,000 dilution.
Fig2: ICC staining SCNN1G in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining SCNN1G in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-SCNN1G antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-SCNN1G antibody. Counter stained with hematoxylin.
Fig6: Flow cytometric analysis of 293T cells with SCNN1G antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
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