Anti-IGLC2 antibody [E12-B9]

Anti-IGLC2 antibody [E12-B9]

• 概述

• 产品描述Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen .

• 产品名称Anti-IGLC2 antibody [E12-B9]

• 分子量11 kDa

• 种属反应性Human

• 验证应用WB,IHC-P

• 抗体类型小鼠单抗

• 免疫原Recombinant protein

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度2 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG1

• 纯化方式Protein A purified.

• 亚细胞定位Secreted, Cell membrane.

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• 其它名称

  more

  • Ig lambda chain C regions antibody

  • IGLC antibody

  • immunoglobulin lambda constant region 2 (Kern- Oz- marker) antibody

• 应用

  WB: 1:500
  IHC-P: 1:50-1:200

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  Fig1: Western blot analysis of IGLC2 on human IGLC2 recombinant protein using anti-IGLC2 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of IGLC2 on HEK293 (1) and IGLC2-hIgGFc transfected HEK293 (2) cell lysate using anti-IGLC2 antibody at 1/1,000 dilution.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human colon tissues using anti-IGLC2 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue using anti-IGLC2 antibody. Counter stained with hematoxylin.

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