Anti-SERPINA7 antibody [E9-B11]

Anti-SERPINA7 antibody [E9-B11]

• 概述

• 产品描述There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

• 产品名称Anti-SERPINA7 antibody [E9-B11]

• 分子量46 kDa

• 种属反应性Human

• 验证应用WB,ICC,IHC-P,FC

• 抗体类型小鼠单抗

• 免疫原Recombinant protein

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度2 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG1

• 纯化方式Protein A purified.

• 亚细胞定位Secreted.

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• ​其它名称

  more

  • Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody

  • Serpin A7 antibody

  • Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody

• 应用

  WB: 1:500-1:2,000
  ICC: 1:100-1:200
  IHC-P: 1:100-1:200
  FC: 1:100-1:200

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  Fig1: Western blot analysis of SERPINA7 on human SERPINA7 recombinant protein using anti-SERPINA7 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of SERPINA7 on HEK293 (1) and SERPINA7-hIgGFc transfected HEK293 (2) cell lysate using anti-SERPINA7 antibody at 1/1,000 dilution.

   

  

  Fig3: ICC staining SERPINA7 (green) in A431 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-SERPINA7 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded human bladder cancer tissue using anti-SERPINA7 antibody. Counter stained with hematoxylin.

   

  

  Fig6: Flow cytometric analysis of A431 cells with SERPINA7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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