Anti-KLHL21 antibody [F4-H4]

Anti-KLHL21 antibody [F4-H4]

• 概述

• 产品描述Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
• 产品名称Anti-KLHL21 antibody [F4-H4]
• 分子量66 kDa
• 种属反应性Human
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm.
• 其它名称
  • Kelch-like protein 21 antibody
  • KIAA0469 antibody
  • KLH21_HUMAN antibody
  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:50-1:200

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  Fig1: Western blot analysis of KLHL21 on human KLHL21 recombinant protein using anti-KLHL21 antibody at 1/1,000 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-KLHL21 antibody. Counter stained with hematoxylin.

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