Anti-ADD1 antibody [H1-D4]

Anti-ADD1 antibody [H1-D4]

• 概述

• 产品描述Adducins are a family of cytoskeleton proteins encoded by three genes (α, β, γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.
• 产品名称Anti-ADD1 antibody [H1-D4]
• 分子量81 kDa
• 种属反应性Human
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm, cytoskeleton, cell membrane
  
• 其它名称
  • ADD A antibody
  • ADD1 antibody
  • ADDA antibody
  more

• 应用

  WB: 1:500-1:2,000
  IHC-P: 1:50-1:200

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  Fig1: Western blot analysis of alpha Adducin on human alpha Adducin recombinant protein using anti- alpha Adducin antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of alpha Adducin on HEK293 (1) and alpha Adducin -hIgGFc transfected HEK293 (2) cell lysate using anti- alpha Adducin antibody at 1/1,000 dilution.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti- alpha Adducin antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti- alpha Adducin antibody. Counter stained with hematoxyli

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