Anti-ARL13B antibody [A4E4]

Anti-ARL13B antibody [A4E4]

• 概述

• 产品描述Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidence is required to confirm these data.
• 产品名称Anti-ARL13B antibody [A4E4]
• 分子量Predicted band size: 49 kDa.
• 种属反应性Human
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原Synthetic peptide within human ARL13B aa 370-428.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein G affinity purified.
• 亚细胞定位Cell membrane, Cell projection, Cilium, Membrane.
• 其它名称
  • ADP ribosylation factor like 13B antibody
  • ADP ribosylation factor like 2 like 1 antibody
  • ADP-ribosylation factor-like protein 13B antibody
  more

• 应用

  WB: 1:500-1:2,000

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  Fig1: Western blot analysis of ARL13B on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody (HA1006) at 1:5,000 dilution was used for 1 hour at room temperature.
  Positive control:
  Lane 1: 293T cell lysate
  Lane 2: HL-60 cell lysate

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