Anti-SST antibody [E7-G5]
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概述
- 产品描述Somatostatin is a regulatory hormone that is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G protein-coupled somatostatin receptors. This cyclic tetradecapeptide inhibits the secretion of many important hormones, including somatotropin (also designated growth hormone, or GH), insulin and glucagon. Somatostatin is found in both the hypothalamus and pancreas. Somatostatin is thought to be involved in the regulation of insulin synthesis. The hormone somatostatin has active 14 amino acid and 28 amino acid forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. In the cerebellum, Somatostatin-14 and Somatostatin-28 are highly expressed at birth and in the adult stage, respectively. Somatostatin affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. The gene encoding Somatostatin maps to human chromosome 3q27.
- 产品名称Anti-SST antibody [E7-G5]
- 分子量13 kDa
- 种属反应性Human
- 验证应用WB,IHC-P,FC
- 抗体类型小鼠单抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
- 亚型IgG1
- 纯化方式Protein A purified.
- 亚细胞定位Secreted.
- 其它名称
- Growth hormone release inhibiting factor antibody
- Growth hormone release-inhibiting factor antibody
- Prepro somatostatin antibody
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应用
WB: 1:500-1:2,000
IHC-P: 1:50-1:200
FC: 1:50-1:200
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Fig1: Western blot analysis of Somatostatin on human Somatostatin recombinant protein using anti- Somatostatin antibody at 1/1,000 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti- Somatostatin antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti- Somatostatin antibody. Counter stained with hematoxylin.
Fig4: Flow cytometric analysis of HepG2 cells with Somatostatin antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
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