Anti-BCL2 antibody [9F1]

Anti-BCL2 antibody [9F1]

• 概述

• 产品描述Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
• 产品名称Anti-BCL2 antibody [9F1]
• 分子量26 kDa
• 种属反应性Human
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Synthetic peptide within human BCL2 35-60 aa.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG
• 纯化方式Peptide affinity purified.
• 亚细胞定位Endoplasmic reticulum. Mitochondrion. Nucleus.
• 其它名称
  • Apoptosis regulator Bcl 2 antibody
  • Apoptosis regulator Bcl-2 antibody
  • Apoptosis regulator Bcl2 antibody
  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:500-1:1,000

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  Fig1: Western blot analysis of BCL2 on THP-1 lysate using anti-BCL2 antibody at 1/500 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-BCL2 antibody. Counter stained with hematoxylin.

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