Anti-Pax8 antibody [6G5]
-
概述
- 产品描述The PAX gene family has an important role in the formation of tissues and organs during embryonic development and maintaining the normal function of some cells after birth. The PAX genes give instructions for making proteins that attach themselves to certain areas of DNA. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. PAX8 releases the hormones important for regulating growth, brain development, and metabolism. Also functions in very early stages of kidney organogenesis, the müllerian system, and the thymus. Additionally, PAX8 is expressed in the renal excretory system, epithelial cells of the endocervix, endometrium, ovary, Fallopian tube, seminal vesicle, epididymis, pancreatic islet cells and lymphoid cells. PAX8 and other transcription factors play a role in binding to DNA and regulating the genes that drive thyroid hormone synthesis (Tg, TPO, Slc5a5 and Tshr). This PAX-8 antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalinfixed, paraffin-embedded tissue sections using IHC test methods.
- 产品名称Anti-Pax8 antibody [6G5]
- 分子量48 kDa
- 种属反应性Human
- 验证应用WB,IHC-P
- 抗体类型小鼠单抗
- 免疫原Synthetic peptide corresponding to human Pax8 aa 400-450.
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG1
- 纯化方式Peptide affinity purified.
- 亚细胞定位Nucleus.
- 其它名称
- OTTHUMP00000158659 antibody
- OTTHUMP00000158660 antibody
- OTTHUMP00000203723 antibody
more
-
应用
WB: 1:500-1:2,000
IHC-P: 1:100-1:200
-
Fig1: Western blot analysis of Pax8 on skov-3 cells lysates using anti-Pax8 antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-Pax8 antibody. Counter stained with hematoxylin.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!