Anti-GSTM1 antibody [A4-H4]

Anti-GSTM1 antibody [A4-H4]

• 概述

• 产品描述Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely alpha, zeta, theta, kappa, mu, pi, sigma and omega, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress.
• 产品名称Anti-GSTM1 antibody [A4-H4]
• 分子量26 kDa
• 种属反应性Human,Monkey
• 验证应用WB,ICC,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm.
• 其它名称
  • EC=2.5.1.18 antibody
  • Glutathione S-transferase Mu 1 antibody
  • GST class-mu 1 antibody
  more

• 应用

  WB: 1:500-1:2,000
  IHC-P: 1:100-1:500
  FC: 1:100-1:200

•  

  

  Fig1: Western blot analysis of GSTM1 on human GSTM1 recombinant protein using anti-GSTM1 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of GSTM1 on different cell lysates using anti-GSTM1 antibody at 1/1,000 dilution.
  Positive control:
  Lane 1: Cos7
  Lane 2: MCF-7
  Lane 3: Jurkat
  Lane 4: Hela
  Lane 5: HL7702
  Lane 6: HepG2

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti-GSTM1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-GSTM1 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Flow cytometric analysis of Jurkat cells with GSTM1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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