Anti-Neuropilin 1 antibody [A3-D1]

Anti-Neuropilin 1 antibody [A3-D1]

• 概述

• 产品描述The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
• 产品名称Anti-Neuropilin 1 antibody [A3-D1]
• 分子量103 kDa
• 种属反应性Human,Mouse
• 验证应用WB,ICC,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgM
• 纯化方式Protein A purified.
• 亚细胞定位Cell membrane
• 其它名称
  • AI851453 antibody
  • BCTL1 antibody
  • Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody
  more

• 应用

  WB: 1:1,000-1:10,000
  ICC: 1:100-1:500
  IHC-P: 1:50

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  Fig1: Western blot analysis on recombinant protein using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).

   

  

  Fig2: Immunofluorescent staining of Hela cells using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).

   

  

  Fig3: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).

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