Anti-UTF1 antibody [E0-F4]

Anti-UTF1 antibody [E0-F4]

• 概述

• 产品描述Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is localized to the cell nucleus, where it functions to regulate the pluripotent chromatin state and buffer mRNA levels by promoting degradation of mRNA. Aberrant expression of UTF1 has also been reported in cervical cancer cells, where the UTF1 gene promoter loses methylation and becomes abnormally expressed compared to normal cervical cells.
• 产品名称Anti-UTF1 antibody [E0-F4]
• 分子量36-50 kDa
• 种属反应性Human,Mouse,Rat
• 验证应用WB,ICC
• 抗体类型小鼠单抗
• 免疫原peptide
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG2b
• 纯化方式Protein A purified.
• 亚细胞定位Nucleus
• 其它名称
  • hUTF 1 antibody
  • hUTF1 antibody
  • Undifferentiated embryonic cell transcription factor 1 antibody
  more

• 应用

  WB: 1:500-1:1,000
  ICC: 1:500-1:1,000

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  Fig1: Western blot analysis on D3 cell lysates using anti- UTF1 mouse mAb.

   

  

  Fig2: ICC staining UTF1 in D3 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

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