Anti-SLC27A5 antibody [C10-B11]

Anti-SLC27A5 antibody [C10-B11]

• 概述

• 产品描述Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.
• 产品名称Anti-SLC27A5 antibody [C10-B11]
• 分子量75 kDa
• 种属反应性Human,Mouse
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Endoplasmic reticulum membrane.
• 其它名称
  • ACSB antibody
  • ACSVL6 antibody
  • BA CoA ligase antibody
  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:100-1:200

•  

  

  Fig1: Western blot analysis of SLC27A5 on human SLC27A5 recombinant protein using anti-SLC27A5 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of SLC27A5 on HEK293 (1) and SLC27A5-hIgGFc transfected HEK293 (2) cell lysate using anti-SLC27A5 antibody at 1/1,000 dilution.

   

  

  Fig3: Western blot analysis of SLC27A5 on 3T3L1 (1) and NIH3T3 (2) cell lysate using anti-SLC27A5 antibody at 1/1,000 dilution.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-SLC27A5 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded human stomach tissue using anti-SLC27A5 antibody. Counter stained with hematoxylin.

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