Anti-L-FABP antibody [AH54-31]

Anti-L-FABP antibody [AH54-31]

• 概述

• 产品描述Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). Liver-specific FABP (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors and is required for cholesterol synthesis and metabolism.
• 产品名称Anti-L-FABP antibody [AH54-31]
• 分子量14 kDa
• 种属反应性Human,Mouse
• 验证应用ICC,ELISA(Cap),WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at -20 ℃. Stable for 12 months from date of receipt.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.08% Sodium Azide.
• 亚型IgG1
• 亚细胞定位Cytoplasm.
• 其它名称
  • FABP 1 antibody
  • FABP1 antibody
  • FABPL antibody
  more

• 应用

  WB: 1:1,000
  ICC: 1:50-1:200
  IHC-P: 1:50-1:200
  ELISA: 1:5,000-1:10,000

•  

  

  Fig1: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

   

  

  Fig6: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

   

  

  Fig7: ICC staining L-FABP in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig8: ICC staining L-FABP in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig9: ICC staining L-FABP in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

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