Anti-UGP2 antibody [7H1]

Anti-UGP2 antibody [7H1] 

• 概述

• 产品描述UGP2 (UDP-glucose pyrophosphorylase 2), also known as UDPG, UGPP2, UDPGP2 or pHC379, is an evolutionarily conserved protein belonging to the UDPGP type 1 family of proteins. Localizing to the cytoplasm, UGP2 forms homooligomers and is believed to function as a glucosyl donor in cellular metabolic pathways. More specifically, UGP2 catalyzes the transfer of a glucose moiety from glucose-1-phosphate to UTP, producing a diphosphate and UDP-glucose. UDP-glucose is an essential precursor for the synthesis of polysaccharides; in liver and muscle, UDP-glucose is a precursor of glycogen, in liver UDP-glucose is also a precursor of UDP-glucuronate, and in lactating mammary gland UDP-glucose is converted to UDP-galactose and then to lactose.
• 产品名称Anti-UGP2 antibody [7H1]
• 分子量57 kDa
• 种属反应性Human,Mouse,Rat
• 验证应用WB,IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein G purified.
• 亚细胞定位Cytoplasm.
• 其它名称
• • pHC379 antibody
  • UDP glucose diphosphorylase antibody
  • UDP glucose pyrophosphorylase 1 antibody
  more

• 应用

  WB: 1:500
  IHC-P: 1:50-1:100
  FC: 1:50-1:100

•  

  

  Fig1: Western blot analysis of UGP2 on human liver tissue lysate using anti-UGP2 antibody at 1/200 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-UGP2 antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-UGP2 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-UGP2 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Flow cytometric analysis of LOVO cells with UGP2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.

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