Anti-CSNK2A2 antibody [A10-E1]

Anti-CSNK2A2 antibody [A10-E1]

• 概述

• 产品描述CSNK2A2 also named CKII. Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Ie, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. Casein kinase II is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
• 产品名称Anti-CSNK2A2 antibody [A10-E1]
• 分子量41 kDa
• 种属反应性Human,Mouse,Rat
• 验证应用WB,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytosol. Nucleus.
• 其它名称
  • Casein kinase 2 alpha prime polypeptide antibody
  • Casein kinase II alpha' chain antibody
  • Casein kinase II subunit alpha' antibody
  more

• 应用

  WB: 1:500-1:1,000
  FC: 1:100-1:200

•  

  

  Fig1: Western blot analysis of CSNK2A2 on human CSNK2A2 recombinant protein using anti-CSNK2A2 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of CSNK2A2 on different cell lysates using anti-CSNK2A2 antibody at 1/1,000 dilution.
  Positive control:
  Lane 1: HeLa
  Lane 2: MCF-7
  Lane 3: HepG2
  Lane 4: Jurkat
  Lane 5: NIH-3T3
  Lane 6: PC-12

   

  

  Fig3: Flow cytometric analysis of HepG2 cells with CSNK2A2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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