Anti-NBR1 antibody [7C3]

Anti-NBR1 antibody [7C3]

• 概述

• 产品描述The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21. 1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
• 产品名称Anti-NBR1 antibody [7C3]
• 分子量120 kDa
• 种属反应性Human, Mouse, Rat
• 验证应用IF, IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant Protein of NBR1
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• 纯化方式Immunogen affinity purified.
• 其它名称
  • Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B) antibody;

• 应用

  IF: 1:50-200
  IHC-P: 1:50-300

•  

  

  Fig1: Immunofluorescence analysis of rat-spleen tissue. 1,NBR1 Mouse Monoclonal Antibody(7C3)(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded Human-liver tissue. 1,NBR1 Mouse Monoclonal Antibody(7C3) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.

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