Anti-PPAR Delta antibody [2F9]

Anti-PPAR Delta antibody [2F9]

• 概述

• 产品描述This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this
• 产品名称Anti-PPAR Delta antibody [2F9]
• 分子量50 kDa
• 种属反应性Human, Rat, Mouse
• 验证应用IF, IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant Protein of PPAR Delta of PPAR Delta
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• 纯化方式Immunogen affinity purified.
• 其它名称
  • Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta) antibody;

• 应用

  IF: 1:50-200
  IHC-P: 1:100-200

•  

  

  Fig1: Immunofluorescence analysis of rat-spleen tissue. 1,PPAR Delta Mouse Monoclonal Antibody(2F9)(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded Human-uterus tissue. 1,PPAR Delta Mouse Monoclonal Antibody(2F9) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.

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