Anti-Kif 7 antibody [3F8]

Anti-Kif 7 antibody [3F8]

• 概述

• 产品描述This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
• 产品名称Anti-Kif 7 antibody [3F8]
• 种属反应性Human, Mouse, Rat
• 验证应用IHC-P, IF
• 抗体类型小鼠单抗
• 免疫原Synthetic Peptide of Kif 7
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
• 纯化方式Immunogen affinity purified.
• 其它名称
  • Kinesin-like protein KIF7 antibody;

• 应用

  IHC-P: 1:50-200
  IF: 1:50-200

•  

  

  Fig1: Immunofluorescence analysis of Mouse-colon tissue. 1,Kif 7 Monoclonal Antibody(3F8)(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

   

  

  Fig2: IHC staining of Mouse Kidney tissue, diluted at 1:200.

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