Anti-OCT-4 antibody
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概述
- 产品描述Oct-4 (POU5F1) is a transcription factor expressed in the totipotent and pluripotent stem cells of the pregastrulation embryo. It is also expressed in primordial germ cells and in the female germ line. OCT4 binds to the octamer motif (5'-ATTTGCAT-3') and forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.
- 产品名称Anti-OCT-4 antibody
- 分子量45kDa
- 种属反应性Human,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Nucleus
- 其它名称
- Octamer binding transcription factor 4 antibody
- MGC22487 antibody
- Oct 3 antibody
more
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Fig1: Western blot analysis on NCCIT (A) and F9 (B) cell lysates using anti-OCT4 rabbit polyclonal antibody.
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