Anti-Bcl-x antibody
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概述
- 产品描述Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2 (2). It has been found that heterodimerization with Bax does not seem to be required for anti-apoptotic activity (3). Since Bcl-xL can form an ion channel in synthetic lipid membranes, there is a strong possibility that this property plays a role in heterodimerization-independent cell survival (4). The Bcl-X(S) isoform promotes apoptosis.
- 产品名称Anti-Bcl-x antibody
- 分子量26 (Bcl-xL) / 19 (Bcl-xS)
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC,IHC-P,FC,IP
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20 ℃. Stable for 12 months from date of receipt
- 存储缓冲液1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein A purified
- 亚细胞定位Cytoplasm, Nucleus membrane, Cytoplasmic vesicle Mitochondrion matrix, Mitochondrion outer/ inner membrane
- 其它名称
- Apoptosis regulator Bcl X antibody
- Bcl 2 like 1 antibody
- Bcl 2 like 1 protein antibody
more
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应用
WB: 1:500-1,000
ICC: 1:100
IHC-P: 1:50-100
IP: 1:10
FC: 1:50
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Fig1: Western blot analysis of K562 cell lysate using anti-Bcl-x.
Fig2: Immunohistochemical analysis of human paraffin-embedded prostate carcinoma tissue using anti-Bcl-x.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
