Anti-BMPR1A antibody
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概述
- 产品描述Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.
- 产品名称Anti-BMPR1A antibody
- 分子量60kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC,IHC-P,FC
- 抗体类型兔多抗
- 免疫原recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Membrane
- 其它名称
- 10q23del antibody
- Activin A receptor type II like kinase 3 antibody
- Activin receptor like kinase 3 antibody
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应用
WB: 1:1,1000
ICC: 1:50-1:200
IHC-P: 1:50-1:200
FC: 1:50-1:100
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Fig1: Western blot analysis on 293 cell lysates using anti-BMPR1A rabbit polyclonal antibody.
Fig2: Immunocytochemical staining of Hela cells using anti-BMPR1A rabbit polyclonal antibody.
Fig3: Immunocytochemical staining of HepG2 cells using anti-BMPR1A rabbit polyclonal antibody.
Fig4: Immunocytochemical staining of SKOV-3 cells using anti-BMPR1A rabbit polyclonal antibody.
Fig5: Immunohistochemical analysis of paraffin- embedded human liver carcinoma tissue using anti-BMPR1A rabbit polyclonal antibody.
Fig6: Immunohistochemical analysis of paraffin- embedded human liver carcinoma tissue using anti-BMPR1A rabbit polyclonal antibody.
Fig7: Immunohistochemical analysis of paraffin- embedded human kidney tissue using anti-BMPR1A rabbit polyclonal antibody.
Fig8: Immunohistochemical analysis of paraffin- embedded mouse skeletal muscle tissue using anti-BMPR1A rabbit polyclonal antibody.
Fig9: Immunohistochemical analysis of paraffin- embedded mouse smooth muscle tissue using anti-BMPR1A rabbit polyclonal antibody.
Fig10: Immunohistochemical analysis of paraffin- embedded mouse kidney tissue using anti-BMPR1A rabbit polyclonal antibody.
Fig11: Flow cytometric analysis of Jurkat cells with BMPR1A antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated Goat anti mouse IgG was used as the secondar
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