Anti-TIMP-1 antibody
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概述
- 产品描述TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases,gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase.TIMP-1 was found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.
- 产品名称Anti-TIMP-1 antibody
- 分子量23 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,IP,IF
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃
- 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Secreted
- 其它名称
- Clgi antibody
- Collagenase inhibitor antibody
- Collagenase inhibitor, Human antibody
more
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应用
WB: 1:1,000
IP: 1-2 μg per 100-500 μg of total protein
IF: 1:50-500
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Fig1: Western blot analysis of TIMP-1 expression in non-transfected(A) and human TIMP-1 transfected (B) 293T whole cell lysates and human recombinant TIMP-1 (C).
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