Anti-CREB1 antibody
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概述
- 产品描述CAMP responsive element binding protein 1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene.This protein binds the cAMP response element, a DNA nucleotide sequence present in many viral and cellular promoters. The binding of CREB1 stimulates transcription.This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins.CREB1 is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
- 产品名称Anti-CREB1 antibody
- 分子量~37kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC,IHC-P
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Nucleus
- 其它名称
- Active transcription factor CREB antibody
- cAMP response element binding protein 1 antibody
- cAMP response element binding protein antibody
more
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应用
WB: 1:500-1:1,000 ICC:1:200-1:500
IHC-P: 1:200
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Fig1: Western blot analysis on A431 (1) and PC12 (2) cell lysates using anti-CREB1 rabbit polyclonal antibodies.
Fig2: Immunofluorescent staining of Hela cells using anti- CREB1 rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti- CREB1 rabbit polyclonal antibody.
Fig4: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti- CREB1 rabbit polyclonal antibody.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
