Anti-GLP1R antibody
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概述
- 产品描述Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both Glucagon and GLP-1 function through their specific binding to the Glucagon receptor or GLP-1R, respectively. The Glucagon receptor shows expression in liver, kidney and adipose tissue. GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.
- 产品名称Anti-GLP1R antibody
- 分子量56 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,IP,IF
- 抗体类型兔多抗
- 免疫原Amino acids 9 1 - 145 mapping within an N-terminal extracellular domain of GLP-1R of human origin.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃
- 存储缓冲液1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Cell membrane
- 其它名称
- GLP 1 R antibody
- GLP 1 receptor antibody
- GLP 1R antibody
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应用
WB: 1:100-1:1,000
IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
IF: 1:50-500
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!