Anti-Rem2 antibody

Anti-Rem2 antibody

• 概述

• 产品描述REM2 (RAS (RAD and GEM)-like GTP binding 2) is a 340 amino acid cell membrane protein that functions as a GTPase and belongs to the RGK family as well as the small GTPase superfamily. A suppressor of the p53 pathway, REM2 also mediates the fibroblastic growth factor 2 (FGF-2) signaling pathway and is involved in maintaining the proliferation of human embryonic stem cells. Expressed in kidney and brain, REM2 is encoded by a gene that maps to human chromosome 14q11.2. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
• 产品名称Anti-Rem2 antibody
• 分子量37 kDa

• 种属反应性Human,Mouse

• 验证应用WB,ICC

• 抗体类型小鼠单抗

• 免疫原recombinant protein

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度2 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG2b

• 纯化方式Protein G purified.

• 亚细胞定位Cell membrane

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• 其它名称

  more

  • FLJ38964 antibody

  • GTP binding protein REM 2 antibody

  • Rad and Gem like GTP binding protein 2 antibody

• 应用

  WB: 1:100-1:500
  ICC: 1:100-1:500

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  Fig1: Western blot analysis on different cell lysates using anti-Rem2 mouse mAb.

   

  

  Fig2: ICC staining Rem2 in NCCIT cells(green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

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