Anti-TNF-IP 8 antibody
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概述
- 产品描述developmental stage:Expressed at high levels in the fetal liver, lung and kidney. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. induction:By nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB. Belongs to the TNFAIP8 family. tissue specificity:Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle.
- 产品名称Anti-TNF-IP 8 antibody
- 分子量23 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human TFIP8. AA range:31-80
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- TNFAIP8 antibody; Tumor necrosis factor alpha-induced protein 8 antibody; TNF alpha-induced protein 8 antibody; Head and neck tumor and metastasis-related protein antibody; MDC-3.13 antibody; NF-kappa-B-inducible DED-containing protein antibody; NDED antibody; SCC-S2 antibody; TNF-induced protein GG2-1 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using TNF-IP 8 Polyclonal Antibody. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
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