Anti-IL-12Rβ1 antibody
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概述
- 产品描述The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
- 产品名称Anti-IL-12Rβ1 antibody
- 分子量73 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the Internal region of human IL12RB1. AA range:211-260
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- IL12RB1 antibody; IL12R antibody; IL12RB antibody; Interleukin-12 receptor subunit beta-1 antibody; IL-12 receptor subunit beta-1 antibody; IL-12R subunit beta-1 antibody; IL-12R-beta-1 antibody; IL-12RB1 antibody; IL-12 receptor beta component antibody; CD212 antibody;
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Fig1: Western Blot analysis of Hela cells using IL-12Rβ1 Polyclonal Antibody.. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
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