Anti-OAS2 antibody
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概述
- 产品描述This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
- 产品名称Anti-OAS2 antibody
- 分子量82 kDa
- 种属反应性Human
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- OAS2 antibody; 2'-5'-oligoadenylate synthase 2 antibody; (2-5')oligo(A) synthase 2 antibody; 2-5A synthase 2 antibody; p69 OAS / p71 OAS antibody; p69OAS / p71OAS antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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