Anti-SP-B antibody

Anti-SP-B antibody

• 概述

• 产品描述This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced trans
• 产品名称Anti-SP-B antibody
• 分子量42 kDa
• 种属反应性Human
• 验证应用WB
• 抗体类型兔多抗
• 免疫原The antiserum was produced against synthesized peptide derived from human SP-B. AA range:243-292
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• 亚型IgG
• 纯化方式Immunogen affinity purified.
• 其它名称
  • SFTPB antibody; SFTP3 antibody; Pulmonary surfactant-associated protein B antibody; SP-B antibody; 18 kDa pulmonary-surfactant protein antibody; 6 kDa protein antibody; Pulmonary surfactant-associated proteolipid SPL(Phe) antibody;

• 应用

  WB: 1:500-1:2000

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  Fig1: Western Blot analysis of various cells using SP-B Polyclonal Antibody diluted at 1：1000

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