Anti-PML antibody
-
概述
- 产品描述The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.
- 产品名称Anti-PML antibody
- 分子量98 kDa
- 种属反应性Human
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human PML. AA range:11-60
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- PML antibody; MYL antibody; RNF71 antibody; TRIM19 antibody; Protein PML antibody; Promyelocytic leukemia protein antibody; RING finger protein 71 antibody; Tripartite motif-containing protein 19 antibody;
-
应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
-
Fig1: Western Blot analysis of various cells using PML Polyclonal Antibody diluted at 1：1000
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
