Anti-Sck antibody
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概述
- 产品描述domain:The PID domain mediates binding to the TrkA receptor. Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. miscellaneous:PubMed:15057824 has shown that SHC2 is poorly phosphorylated by the Trk receptors, in opposite to PubMed:12006576. PTM:Phosphorylated on tyrosines by the Trk receptors. Contains 1 PID domain. Contains 1 SH2 domain. subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2. tissue specificity:Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus.
- 产品名称Anti-Sck antibody
- 分子量59 kDa
- 种属反应性Human,Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human SHC2. AA range:261-310
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SHC2 antibody; SCK antibody; SHCB antibody; SHC-transforming protein 2 antibody; Protein Sck antibody; SHC-transforming protein B antibody; Src homology 2 domain-containing-transforming protein C2 antibody; SH2 domain protein C2 antibody;
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