Anti-Rabaptin-5α antibody
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概述
- 产品描述Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity. Belongs to the rabaptin family. subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.
- 产品名称Anti-Rabaptin-5α antibody
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- RABEP1 antibody; RAB5EP antibody; RABPT5 antibody; RABPT5A antibody; Rab GTPase-binding effector protein 1 antibody; Rabaptin-4 antibody; Rabaptin-5 antibody; Rabaptin-5alpha antibody; Renal carcinoma antigen NY-REN-17 antibody;
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