Anti-FIR antibody

Anti-FIR antibody

• 概述

• 产品描述Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Contains 1 DH (DBL-homology) domain. Contains 1 FERM domain. Contains 2 PH domains. subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.
• 产品名称Anti-FIR antibody
• 分子量119 kDa
• 种属反应性Human, Mouse
• 验证应用WB, IF
• 抗体类型兔多抗
• 免疫原The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• 亚型IgG
• 纯化方式Immunogen affinity purified.
• 其它名称FARP2 antibody; KIAA0793 antibody; PLEKHC3 antibody; FERM antibody; RhoGEF and pleckstrin domain-containing protein 2 antibody; FERM domain including RhoGEF antibody; FIR antibody; Pleckstrin homology domain-containing family C member 3 antibody; PH domain-containing family C member 3 antibody;

• 应用

  WB: 1:500-1:2000
  IF: 1:100-1:500

•  

  

  Fig1: Western Blot analysis of various cells using FIR Polyclonal Antibody

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！