Anti-Flk-1/Flt-4 antibody
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概述
- 产品描述Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. . Mutations of this gene are implicated in infantile capillary hemangiomas.
- 产品名称Anti-Flk-1/Flt-4 antibody
- 种属反应性Human, Mouse, Rat
- 验证应用IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human VEGFR2. AA range:1020-1069
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称KDR antibody; FLK1 antibody; VEGFR2 antibody; Vascular endothelial growth factor receptor 2 antibody; VEGFR-2 antibody; Fetal liver kinase 1 antibody; FLK-1 antibody; Kinase insert domain receptor antibody; KDR antibody; Protein-tyrosine kinase receptor flk-1 antibody; CD antigen CD309 antibody; FLT4 antibody; VEGFR3 antibody; Vascular endothelial growth antibody;
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应用
IHC-P: 1:100-1:300
IF: 1:100-1:500
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Fig1: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using VEGFR2 Antibody. The picture on the right is blocked with the synthesized peptide.
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