Anti-GFRα-1 antibody
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概述
- 产品描述This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
- 产品名称Anti-GFRα-1 antibody
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P,WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human GFR alpha-1. AA range:51-100
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称GFRA1 antibody; GDNFRA antibody; RETL1 antibody; TRNR1 antibody; GDNF family receptor alpha-1 antibody; GDNF receptor alpha-1 antibody; GDNFR-alpha-1 antibody; GFR-alpha-1 antibody; RET ligand 1 antibody; TGF-beta-related neurotrophic factor receptor 1 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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