Anti-COL4A4 antibody
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概述
- 产品描述This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR.
- 产品名称Anti-COL4A4 antibody
- 种属反应性Human
- 验证应用IHC-P,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Collagen IV alpha4. AA range:541-590
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称COL4A4 antibody; Collagen alpha-4(IV) chain antibody;
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应用
IHC-P: 1:100-1:300
IF: 1:100-1:500
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