Anti-Gab 2 antibody
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概述
- 产品描述This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
- 产品名称Anti-Gab 2 antibody
- 分子量97 kDa
- 种属反应性Human,Mouse,Rat,Monkey
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Gab2. AA range:125-174
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称GAB2 antibody; KIAA0571 antibody; GRB2-associated-binding protein 2 antibody; GRB2-associated binder 2 antibody; Growth factor receptor bound protein 2-associated protein 2 antibody; pp100 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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