Anti-DOC-1 antibody
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概述
- 产品描述The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- 产品名称Anti-DOC-1 antibody
- 分子量20 kDa
- 种属反应性Human, Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human CDKAP1. AA range:51-100
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称CDK2AP1 antibody; CDKAP1 antibody; DOC1 antibody; Cyclin-dependent kinase 2-associated protein 1 antibody; CDK2-associated protein 1 antibody; Deleted in oral cancer 1 antibody; DOC-1 antibody; Putative oral cancer suppressor antibody;
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Fig1: Western Blot analysis of various cells using DOC-1 Polyclonal Antibody diluted at 1:500
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!