Anti-CA VIII antibody
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概述
- 产品描述The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i. e. the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid
- 产品名称Anti-CA VIII antibody
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from the Internal region of human CA VIII.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 数据链接SwissProt: P35219 Huma其它名称
- CA8 antibody; CALS antibody; Carbonic anhydrase-related protein antibody; CARP antibody; Carbonic anhydrase VIII antibody; CA-VIII antibody;
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