Anti-ZDH17 antibody
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概述
- 产品描述catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA. domain:The DHHC domain is required for palmitoyltransferase activity. Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Has transforming activity. miscellaneous:The early and prominent pathology of HD is observed in the medium spiny neurons that project into the globus. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. Contains 1 DHHC-type zinc finger. Contains 5 ANK repeats. subunit:Binds HD. This interaction is inversely correlated to the length of the polyglutamine tract added to the huntingtin protein in Huntington disease. tissue specificity:Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney.
- 产品名称Anti-ZDH17 antibody
- 分子量69 kDa
- 种属反应性Human,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from part region of human protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
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特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
