Anti-Kv1.8 antibody
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概述
- 产品描述Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA
- 产品名称Anti-Kv1.8 antibody
- 分子量58 kDa
- 种属反应性Human, Rat, Mouse
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthetic Peptide of Kv1.8
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称Potassium voltage-gated channel subfamily A member 10 (Voltage-gated potassium channel subunit Kv1.8) antibody;
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应用
WB: 1:1000-1:2000
IHC-P: 1:100-200
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Fig1: Western blot analysis of 1) Rat Brain Tissue, 2)Mouse Brain Tissue with KV1.8 Rabbit pAb diluted at 1:2,000.
Fig2: Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using Kv1.8 Rabbit pAb diluted at 1:200.
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