Anti-GLP1R antibody
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概述
- 产品描述This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
- 产品名称Anti-GLP1R antibody
- 分子量53 kDa
- 种属反应性Human, Rat, Mouse
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthetic Peptide of GLP1R
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称GLP1R antibody; Glucagon-like peptide 1 receptor antibody; GLP-1 receptor antibody; GLP-1-R antibody; GLP-1R antibody;
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应用
WB: 1:500-1:1000
IHC-P: 1:50-100
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Fig1: Western blot analysis of 1) Rat BrainTissue, 2)Mouse Brain Tissue with GLP1R Rabbit pAb diluted at 1:2,000.
Fig2: Immunohistochemical analysis of paraffin-embedded Human Pancreas Tissue using GLP1R Rabbit pAb diluted at 1:200.
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