Anti-GABA A Receptor α4 antibody
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概述
- 产品描述Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.,
- 产品名称Anti-GABA A Receptor α4 antibody
- 分子量62 kDa
- 种属反应性Human, Rat, Mouse
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthetic Peptide of GABA A Receptor α4
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称GABRA4 antibody; Gamma-aminobutyric acid receptor subunit alpha-4 antibody; GABA(A) receptor subunit alpha-4 antibody;
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应用
WB: 1:1000-1:2000
IHC-P: 1:100-200
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Fig1: Western blot analysis of 1) Mouse Brain Tissue, 2)Rat Brain Tissue with GABA A Receptor α4 Rabbit pAb diluted at 1:2,000.
Fig2: Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using GABA A Receptor α4 Rabbit pAb diluted at 1:200.
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