Anti-RAD51D antibody
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概述
- 产品描述Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.
- 产品名称Anti-RAD51D antibody
- 分子量35 KDa
- 种属反应性Human,Mouse,Cow
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human RAD51D 1-100/328
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Nucleus.
- 其它名称BROVCA4
DNA repair protein RAD51 homolog 4
HsTRAD
OTTHUMP00000163851
OTTHUMP00000163852
OTTHUMP00000163853
R51H3
RA51D_HUMAN
RAD51 homolog D (S. cerevisiae)
RAD51 homolog D
RAD51 like 3 (S. cerevisiae)
RAD51 paralog D
RAD51, S. cerevisiae, homolog of, D
RAD51-like protein 3
Rad51l3
Recombination repair protein
S. cerevisiae RAD51-like 3
TRAD.
more
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Fig1: Sample: Hela Cell (Human) Lysate at 30 ug
Primary: Anti-RAD51D at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 35kD
Observed band size: 30kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
