Anti-CASC5 antibody
-
概述
- 产品描述Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
- 产品名称Anti-CASC5 antibody
- 分子量265 KDa
- 种属反应性Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human CASC5 2251-2342/2342
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Nucleus. Chromosome, centromere, kinetochore.
- 其它名称Protein D40/AF15q14
AF15Q14
ALL1 fused gene from chromosome 15q14
Blinkin bub linking kinetochore protein
Cancer susceptibility candidate 5
Cancer susceptibility candidate gene 5 protein
Cancer/testis antigen 29
CT29
D40
hKNL 1
hSpc105
KIAA1570
Kinetochore null 1 homolog
Kinetochore null protein 1
KNL1
CASC5_HUMAN.
more
-
-
Fig1: Sample:
K562(Human) Cell Lysate at 30 ug
Primary: Anti- CASC5 at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 265 kD
Observed band size: 265 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
