Anti-IL12B antibody
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概述
- 产品描述Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- 产品名称Anti-IL12B antibody
- 分子量37 kDa
- 种属反应性Human,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthetic peptide within mouse IL12B 220-300 aa.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified.
- 亚细胞定位Secreted.
- 其它名称CLMF antibody
CLMF p40 antibody
CLMF2 antibody
Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody
IL 12B antibody
IL-12 subunit p40 antibody
IL-12B antibody
IL12 p40 antibody
IL12B antibody
IL12B_HUMAN antibody
IMD28 antibody
IMD29 antibody
Interleukin 12 beta chain antibody
Interleukin 12 p40 antibody
Interleukin-12 subunit beta antibody
NK cell stimulatory factor chain 2 antibody
NKSF antibody
NKSF2 antibody
more
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Fig1: s of IL12B on different lysates using anti-IL12B antibody at 1/500 dilution.
Positive control:
Lane 1: Hela
Lane 2: Mouse placenta
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
