Anti-CYP3A1 antibody
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概述
- 产品描述In animals, P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. Cytochrome P450 3A4 [human-3A1 Rat] is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
- 产品名称Anti-CYP3A1 antibody
- 分子量57 KDa
- 种属反应性Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from rat CYP3A1 231-330/504
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Endoplasmic reticulum, membrane bound.
- 其它名称Cytochrome P450 3A1
CYP3A
CYP3A1
cytochrome P450, family 3, subfamily a, polypeptide 1
glucocorticoid inducible P450
HLP
MGC126680
NF 25
NF25
Nifedipine oxidase
Niphedipine oxidase
P450 III steroid inducible
P450 PCN(PCNC inducible)
P450 PCN1
P450C3
P450PCN1
Quinine 3 monooxygenase
Taurochenodeoxycholate 6 alpha hydroxylase
CP3A1_RAT.
more
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Fig1: Sample:
Liver (Rat)Lysate at 40 ug
Cerebrum (Rat)Lysate at 40 ug
Primary: Anti-CYP3A1at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 57kD
Observed band size: 57kD
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!